University of Cagliari
Melania Melis
Human perception of coffee aroma and its odor-active molecules: role of the olfactory threshold and the OBPIIa gene
2026-01-01 Diana, D.; Melis, Melania.; Solari, P.; Tomassini Barbarossa, I.; Crnjar, R.; Sollai, G.
Cranberry Polyphenol Extract (CPE) Oral Rinse Improves Salivary Microbiome in 6-n-Propylthiouracil (PROP) Non-Tasters and Palatability of Aronia Juice
2026-01-01 Nguyen-DeMary, Katrina; Vascellari, Sarah; Mastinu, Mariano; Melis, Melania; Bastiaanssen, Thomaz F. S.; Tomassini Barbarossa, Iole; Tepper, Beverly J.
Sex-Specific Patterns of Taste Dysfunction, Their Relationships with α-Synuclein Profiling, and Supervised Learning-Based Diagnosis in Parkinson’s Disease (PD)
2026-01-01 Melis, Melania; Angius, Fabrizio; Naciri, Lala Chaimae; Sollai, Giorgia; Deligia, Silvia; Fenu, Giuseppe; Mellino, Paolo; Pinna, Beatrice; Crnjar, Roberto; Carta, Anna R.; Cossu, Giovanni; Tomassini Barbarossa, Iole
Automatic detection of fungiform papillae on the human tongue via Convolutional Neural Networks and identification of the best performing model
2025-01-01 Naciri, L. C.; Cabini, R. F.; Melis, M.; Crnjar, R.; Pizzagalli, D. U.; Tomassini Barbarossa, I.
TAS2R38 gene methylation is associated with syndrome Coronavirus 2 (SARS-CoV-2) infection and clinical symptoms
2025-01-01 Melis, M.; Loi, E.; Aru, G.; Sollai, G.; Mastinu, M.; Naciri, L. C.; De Riu, G.; Vaira, L. A.; Costanzo, G.; Firinu, D.; Cabras, P.; Caddori, A.; Crnjar, R.; Zavattari, P.; Tomassini Barbarossa, I.
A multi-dimensional study on taste deficits, α-synuclein genetic profiling, and supervised learning for diagnosis and disease severity stratification in Parkinson's disease (PD)
2025-01-01 Naciri, Lala Chaimae; Melis, Melania; Sollai, Giorgia; Deligia, Silvia; Fenu, Giuseppe; Mellino, Paolo; Pinna, Beatrice; Crnjar, Roberto; Cossu, Giovanni; Barbarossa, Iole Tomassini
Methods for fungiform papillae assessment: A collaborative study among European research units
2024-01-01 Piochi, Maria; Spinelli, Sara; Melis, Melania; Laureati, Monica; Feeney, Emma; Methven, Lisa; Yang, Qian; Monteleone, Erminio; Torri, Luisa; Ford, Rebecca; Pagliarini, Ella; Barbarossa, Iole Tomassini; Dinnella, Caterina.
Gene Methylation Affects Salivary Levels of the Taste Buds' Trophic Factor, Gustin Protein
2024-01-01 Melis, Melania; Loi, Eleonora; Mastinu, Mariano; Naciri, LALA CHAIMAE; Zavattari, Patrizia; TOMASSINI BARBAROSSA, Iole
Effect of the rs2821557 Polymorphism of the Human Kv1.3 Gene on Olfactory Function and BMI in Different Age Groups
2024-01-01 Melis, Melania; Mastinu, M.; Sollai, G.
A Supervised Learning Regression Method for the Analysis of the Taste Functions of Healthy Controls and Patients with Chemosensory Loss
2023-01-01 Naciri, L. C.; Mastinu, M.; Melis, Melania; Green, T.; Wolf, A.; Hummel, T.; Tomassini Barbarossa, I.
The Implications of Taste and Olfaction in Nutrition and Health
2023-01-01 Melis, Melania; Tomassini Barbarossa, I.; Sollai, G.
Automated identification of the genetic variants of TAS2R38 bitter taste receptor with supervised learning
2023-01-01 Naciri, L. C.; Mastinu, M.; Crnjar, R.; Barbarossa, I. T.; Melis, M.
A supervised learning regression method for the analysis of oral sensitivity of healthy individuals and patients with chemosensory loss
2023-01-01 Naciri, L. C.; Mastinu, M.; Melis, Melania; Green, T.; Wolf, A.; Hummel, T.; Barbarossa, I. T.
Emotional responses to taste and smell stimuli: Self-reports, physiological measures, and a potential role for individual and genetic factors
2022-01-01 Mastinu, Mariano; Melis, Melania; Yousaf, Neeta Y; Barbarossa, Iole Tomassini; Tepper, Beverly J
A polymorphism in the human gene encoding OBPIIa affects the perceived intensity of smelled odors
2022-01-01 Sollai, G.; Melis, M.; Tomassini Barbarossa, I.; Crnjar, R.
Associations between Sweet Taste Sensitivity and Polymorphisms (SNPs) in the TAS1R2 and TAS1R3 Genes, Gender, PROP Taster Status, and Density of Fungiform Papillae in a Genetically Homogeneous Sardinian Cohort
2022-01-01 Melis, Melania; Mastinu, Mariano; Naciri, LALA CHAIMAE; Muroni, Patrizia; TOMASSINI BARBAROSSA, Iole
Daily Exposure to a Cranberry Polyphenol Oral Rinse Alters the Oral Microbiome but Not Taste Perception in PROP Taster Status Classified Individuals
2022-01-01 Yousaf, Neeta Y; Wu, Guojun; Melis, Melania; Mastinu, Mariano; Contini, Cristina; Cabras, Tiziana; Tomassini Barbarossa, Iole; Zhao, Liping; Lam, Yan Y; Tepper, Beverly J
Olfactory Sensitivity Is Associated with Body Mass Index and Polymorphism in the Voltage-Gated Potassium Channels Kv1.3
2022-01-01 Melis, Melania; TOMASSINI BARBAROSSA, Iole; Crnjar, Roberto; Sollai, Giorgia
Automated Classification of 6-n-Propyltiouracil Taster Status with Machine Learning
2022-01-01 Naciri, L. C.; Mastinu, M.; Crnjar, R.; Barbarossa, I. T.; Melis, M.
Molecular and genetic factors involved in olfactory and gustatory deficits and associations with microbiota in parkinson’s disease
2021-01-01 Melis, M.; Haehner, A.; Mastinu, M.; Hummel, T.; Barbarossa, I. T.
Effect of the rs2890498 polymorphism of the OBPIIa gene on the human ability to smell single molecules
2021-01-01 Melis, M.; Tomassini Barbarossa, I.; Hummel, T.; Crnjar, R.; Sollai, G.
Differences in salivary proteins as a function of prop taster status and gender in normal weight and obese subjects
2021-01-01 Melis, Melania; Mastinu, Mariano; Pintus, Stefano; Cabras, Tiziana; Crnjar, ROBERTO MASSIMO; TOMASSINI BARBAROSSA, Iole
Olfactory Function in Patients with Inflammatory Bowel Disease (IBD) Is Associated with Their Body Mass Index and Polymorphism in the Odor Binding Protein (OBPIIa) Gene
2021-01-01 Sollai, Giorgia; Melis, Melania; Mastinu, Mariano; Paduano, Danilo; Chicco, Fabio; Magri', Salvatore; Usai, Paolo; Hummel, Thomas; TOMASSINI BARBAROSSA, Iole; Crnjar, ROBERTO MASSIMO
Changes of taste, smell and eating behavior in patients undergoing bariatric surgery: Associations with prop phenotypes and polymorphisms in the odorant-binding protein OBPIIa and CD36 receptor genes
2021-01-01 Melis, M.; Pintus, S.; Mastinu, M.; Fantola, G.; Moroni, R.; Pepino, M. Y.; Tomassini Barbarossa, I.
Imaging and Genomic Classification of Brain Alteration Induced By Gustatory Bitter Stimulus, A Pilot Study
2020-01-01 Barberini, Luigi; TOMASSINI BARBAROSSA, Iole; Melis, Melania; Marrosu, Francesco; Siotto, Paolo; Saba, Luca
Taste Changes in Patients with Inflammatory Bowel Disease: Associations with PROP Phenotypes and polymorphisms in the salivary protein, Gustin and CD36 Receptor Genes
2020-01-01 Melis, M.; Mastinu, M.; Sollai, G.; Paduano, D.; Chicco, F.; Magri, S.; Usai, P.; Crnjar, R.; Tepper, B. J.; Tomassini Barbarossa, I.
Electrophysiological Responses from the Human Tongue to the Six Taste Qualities and Their Relationships with PROP Taster Status
2020-01-01 Melis, M.; Sollai, G.; Mastinu, M.; Pani, D.; Cosseddu, P.; Bonfiglio, A.; Crnjar, R.; Tepper, B. J.; Barbarossa, I. T.
“Smelling and Tasting” Parkinson's Disease: Using Senses to Improve the Knowledge of the Disease
2020-01-01 Oppo, V.; Melis, M.; Melis, M.; Tomassini Barbarossa, I.; Cossu, G.
Time course of salivary protein responses to cranberry-derived polyphenol exposure as a function of PROP taster status
2020-01-01 Yousaf, N. Y.; Melis, M.; Mastinu, M.; Contini, C.; Cabras, T.; Barbarossa, I. T.; Tepper, B. J.
Genetic variants of TAS2R38 bitter taste receptor associate with distinct gut microbiota traits in Parkinson's disease: A pilot study
2020-01-01 Vascellari, Sarah; Melis, Melania; Cossu, Giovanni; Melis, Marta; Serra, Alessandra; Palmas, Vanessa; Perra, Daniela; Oppo, Valentina; Fiorini, Michele; Cusano, Roberto; Morelli, Micaela; Manzin, Aldo; Barbarossa, Iole Tomassini
Association between the rs2590498 polymorphism of Odorant Binding Protein (OBPIIa) gene and olfactory performance in healthy subjects
2019-01-01 Sollai, Giorgia; Melis, Melania; Magri', Salvatore; Usai, Paolo; Thomas, Hummel; TOMASSINI BARBAROSSA, Iole; Crnjar, ROBERTO MASSIMO
Taste disorders are partly genetically determined: Role of the TAS2R38 gene, a pilot study
2019-01-01 Melis, Melania; Grzeschuchna, Lisa; Sollai, Giorgia; Hummel, Thomas; Tomassini Barbarossa, Iole
Odor identification performance in idiopathic Parkinson’s disease is associated with gender and the genetic variability of the olfactory binding protein
2019-01-01 Melis, M.; Sollai, G.; Masala, C.; Pisanu, C.; Cossu, G.; Melis, M.; Sarchioto, M.; Oppo, V.; Morelli, M.; Crnjar, R.; Hummel, T.; Barbarossa, I.
TAS2R38 bitter taste receptor and attainment of exceptional longevity
2019-01-01 Melis, M.; Errigo, A.; Crnjar, R.; Pes, G. M.; Tomassini Barbarossa, I.
Human tongue electrophysiological response to oleic acid and its associations with PROP taster status and the CD36 polymorphism (rs1761667)
2019-01-01 Sollai, Giorgia; Melis, Melania; Mastinu, Mariano; Pani, Danilo; Cosseddu, Piero; Bonfiglio, Annalisa; Crnjar, Roberto; Tepper, Beverly J.; Barbarossa, Iole Tomassini
A novel objective method for human gustatory sensitivity assessment
2018-01-01 Pani, D.; Martis, ALICE EVELINA; Sulas, E.; Cosseddu, P.; Usai, I.; Moi, Veronica; Melis, M.; Sollai, G.; Crnjar, R.; Tomassini Barbarossa, I.; Bonfiglio, A.
6-n-propylthiouracil taste disruption and TAS2R38 nontasting form in Parkinson's disease
2018-01-01 Cossu, Giovanni; Melis, Melania; Sarchioto, Marianna; Melis, Marta; Melis, Maurizio; Morelli, Micaela; Tomassini Barbarossa, Iole
Effect of chemical interaction between oleic acid and L-Arginine on oral perception, as a function of polymorphisms of CD36 and OBPIIa and genetic ability to taste 6-n-propylthiouracil
2018-01-01 Melis, Melania; Mastinu, Mariano; Arca, Massimiliano; Crnjar, Roberto; Tomassini Barbarossa, Iole
Effects of CD36 Genotype on Oral Perception of Oleic Acid Supplemented Safflower Oil Emulsions in Two Ethnic Groups: A Preliminary Study
2018-01-01 Burgess, Brenda; Melis, Melania; Scoular, Katelyn; Driver, Michael; Schaich, Karen M.; Keller, Kathleen L.; Tomassini Barbarossa, Iole; Tepper, Beverly J.
Networks in the brain: from neurovascular coupling of the BOLD effect to brain functional architecture
2017-01-01 Barberini, Luigi; Marrosu, Francesco; Tommasini Barbarossa, Iole; Melis, Melania; Suri, Harman S.; Mandas, Antonella; Suri, Jashit S.; Balestrieri, Antonella; Anzidei, Michele; Saba, Luca
Electrophysiological recordings from the tongue for the objective evaluation of individual variations of 6-n-propylthiouracil (PROP) sensitivity
2017-01-01 Melis, Melania; Sollai, Giorgia; Pani, Danilo; Cosseddu, Piero; Crnjar, ROBERTO MASSIMO; Bonfiglio, Annalisa; TOMASSINI BARBAROSSA, Iole
OBJECTIVE EVALUATION OF THE GUSTATORY SENSITIVENESS OF PATIENTS BY THE ELECTROPHYSIOLOGICAL RECORDING OF THE RESPONSE OF BUD CELLS TO TASTE STIMULI.
2017-01-01 Melis, Melania; Sollai, Giorgia; Pani, Danilo; Cosseddu, Piero; Bonfiglio, Annalisa; Crnjar, ROBERTO MASSIMO; TOMASSINI BARBAROSSA, Iole
DEVICE, SYSTEM AND RELATING METHOD FOR THE QUANTITATIVE ASSESSMENT OF TASTE SENSITIVITY
2017-01-01 Tomassini Barbarossa, I.; Crnjar, R. M.; Sollai, G.; Melis, M.; Pani, D.; Cosseddu, P.; Bonfiglio, A
Variant in a common odorant-binding protein gene is associated with bitter sensitivity in people
2017-01-01 TOMASSINI BARBAROSSA, Iole; Ozdener, M. Hakan; Melis, Melania; Love Gregory, Latisha; Mitreva, Makedonka; Abumrad, Nada A.; Pepino, M. Yanina
First objective evaluation of taste sensitivity to 6-n-propylthiouracil (PROP), a paradigm gustatory stimulus in humans
2017-01-01 Sollai, Giorgia; Melis, Melania; Pani, Danilo; Cosseddu, Piero; Usai, Ilenia; Crnjar, ROBERTO MASSIMO; Bonfiglio, Annalisa; TOMASSINI BARBAROSSA, Iole
Factors influencing the phenotypic characterization of the oral marker, PROP
2017-01-01 Tepper, Beverly J.; Melis, Melania; Koelliker, Yvonne; Gasparini, Paolo; Ahijevych, Karen L.; Barbarossa, Iole Tomassini
Taste perception of sweet, sour, salty, bitter, and Umami and changes due to L-arginine supplementation, as a function of genetic ability to taste 6-n-propylthiouracil
2017-01-01 Melis, Melania; TOMASSINI BARBAROSSA, Iole
An automated system for the objective evaluation of human gustatory sensitivity using tongue biopotential recordings
2017-01-01 Pani, Danilo; Usai, Ilenia; Cosseddu, Piero; Melis, Melania; Sollai, Giorgia; Crnjar, ROBERTO MASSIMO; TOMASSINI BARBAROSSA, Iole; Raffo, Luigi; Bonfiglio, Annalisa
Sensory perception of and salivary protein response to astringency as a function of the 6-n-propylthioural (PROP) bitter-taste phenotype
2017-01-01 Melis, Melania; Yousaf, Neeta Y; Mattes, Mitchell Z; Cabras, Tiziana; Messana, Irene; Crnjar, ROBERTO MASSIMO; TOMASSINI BARBAROSSA, Iole; Tepper, Beverly J.
Polymorphism rs1761667 in the CD36 gene is associated to changes in fatty acid metabolism and circulating endocannabinoid levels distinctively in normal weight and obese subjects
2017-01-01 Melis, Melania; Carta, Gianfranca; Pintus, Stefano; Pintus, Paolo; Piras, Carla A.; Murru, Elisabetta; Manca, Claudia; Di Marzo, Vincenzo; Banni, Sebastiano; Barbarossa, Iole Tomassini
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