University of Cagliari
Francesca Esposito
2‐Phenylquinolines Exhibit Anti‐Severe Acute Respiratory Syndrome Coronavirus‐2 Activity Through the Nonstructural Protein 13 Helicase Inhibition
2026-01-01 Cernicchi, Giada; Nizi, Maria Giulia; Emmolo, Roberta; Persoons, Leentje; Laporte, Manon; Jochmans, Dirk; Romeo, Isabella; Pepe, Giacomo; Milite, Ciro; Campiglia, Pietro; Spezzini, Jacopo; Martelli, Alma; Brogi, Simone; Esposito, Francesca; Felicetti, Tommaso; Massari, Serena; Manfroni, Giuseppe; Sabatini, Stefano; Sbardella, Gianluca; Alcaro, Stefano; Neyts, Johan; Corona, Angela; Tramontano, Enzo; De Jonghe, Steven; Tabarrini, Oriana
Special Issue “Advances in Antiviral Agents Against SARS-CoV-2 and Its Variants” 2nd Edition
2026-01-01 Esposito, Francesca
Thiol-Reactive or Redox-Active: Revising a Repurposing Screen Led to a New Invalidation Pipeline and Identified a True Noncovalent Inhibitor Against Papain-like Protease from SARS-CoV-2
2025-01-01 Kuzikov, Maria; Morasso, Stefano; Reinshagen, Jeanette; Wolf, Markus; Monaco, Vittoria; Cozzolino, Flora; Golič Grdadolnik, Simona; Šket, Primož; Plavec, Janez; Iaconis, Daniela; Summa, Vincenzo; Corona, Angela; Paulis, Annalaura; Esposito, Francesca; Tramontano, Enzo; Monti, Maria; Beccari, Andrea R.; Manelfi, Candida; Windshügel, Björn; Gribbon, Philip; Storici, Paola; Zaliani, Andrea
Identifying potential allosteric inhibitors of ZIKV NS3pro through a combined computational and biochemical approach
2025-01-01 Demuru, L.; Lupia, A.; Nieddu, S.; Emmolo, R.; Paulis, A.; Esposito, F.; Distinto, S.; Bryant, S. D.; Onali, A.; Sanna, E.; Atzeni, G.; Cottiglia, F.; Grandi, N.; Corona, A.; Tramontano, E.; Maccioni, E.; Meleddu, R.
2-(Trihydroxyphenyl)thienopyrimidinones as Key Scaffolds for Targeting a Novel Allosteric Site of HIV-1 Integrase
2025-01-01 Tocco, Graziella; Laus, Antonio; Casula, Mattia; Caboni, Pierluigi; Beutler, John A.; Tramontano, Enzo; Esposito, Francesca
Cys44 of SARS-CoV-2 3CLpro affects its catalytic activity
2025-01-01 Iacobucci, I.; Cipollone, I.; Cozzolino, F.; Iaconis, D.; Talarico, C.; Coppola, G.; Morasso, S.; Costanzi, E.; Malune, Paolo; Storici, P.; Tramontano, E.; Esposito, Francesca; Monti, M.
The efficiency of high-throughput screening (HTS) and in-silico data analysis during medical emergencies: Identification of effective antiviral 3CLpro inhibitors
2025-01-01 Zian, D.; Iaconis, D.; Nenci, S.; Crusco, A.; Tawde, S.; Sodano, M.; Vitalone, R.; Raje, A.; Palamini, M.; Carettoni, D.; Molteni, A.; Manelfi, C.; Tazzari, V.; Beccari, A. R.; Malune, P.; Maloccu, S.; Paulis, Annalaura; Corona, Angela; Nieddu, Salvatore; Coletti, S.; Scarabottolo, L.; Tramontano, Enzo; Esposito, Francesca; Catalani, M.
Meeting report: Seventh summer school on innovative approaches for identification of antiviral agents (IAAASS)
2025-01-01 Corona, Angela; Cagno, Valeria; Grandi, Nicole; Fanunza, Elisa; Esposito, Francesca; Seley-Radtke, Kathie L.; Tramontano, Enzo
Dual-Site Inhibition of SARS-CoV2 RNA-Dependent RNA Polymerase by Small Molecules Able to Block Viral Replication Identified through a Computer-Aided Drug Discovery Approach
2025-01-01 Malune, Paolo; Iaconis, Daniela; Manelfi, Candida; Giunta, Stefano; Emmolo, Roberta; Lunghini, Filippo; Paulis, Annalaura; Talarico, Carmine; Corona, Angela; Rosario Beccari, Andrea; Tramontano, Enzo; Esposito, Francesca
Structure−Activity Relationships of New 1‐Aryl‐1H‐Indole Derivatives as SARS‐CoV‐2 Nsp13 Inhibitors
2025-01-01 Madia, Valentina Noemi; Emmolo, Roberta; Patacchini, Elisa; Amatore, Donatella; Maloccu, Stefania; Ialongo, Davide; Albano, Aurora; Ruggieri, Giuseppe; Cara, Emanuele; Zarbo, Laura; Messore, Antonella; De Santis, Riccardo; Amoroso, Alessandra; Lista, Florigio; Esposito, Francesca; Tramontano, Enzo; Corona, Angela; Di Santo, Roberto; Costi, Roberta
N -alkyl and N-benzyl indoles are anti-SARS-CoV-2 agents and nsp13 inhibitors
2025-01-01 Albano, Aurora; Emmolo, Roberta; De Santis, Riccardo; Patacchini, Elisa; Madia, Valentina Noemi; Maloccu, Stefania; Ialongo, Davide; Ruggieri, Giuseppe; Arpacioglu, Merve; Scipione, Luigi; Saccoliti, Francesco; Amatore, Donatella; Grilli, Giorgia; Lista, Florigio; Esposito, Francesca; Tramontano, Enzo; Corona, Angela; Di Santo, Roberto; Costi, Roberta
Unveiling SARS-CoV-2's heart: role, structure and inhibition of SARS-CoV-2 RNA-dependent RNA polymerase
2025-01-01 Malune, P.; Esposito, Francesca; Tramontano, E.
New Thiazolidine-4-One Derivatives as SARS-CoV-2 Main Protease Inhibitors
2024-01-01 Messore, Antonella; Malune, Paolo; Patacchini, Elisa; Noemi Madia, Valentina; Ialongo, Davide; Arpacioglu, Merve; Albano, Aurora; Ruggieri, Giuseppe; Saccoliti, Francesco; Scipione, Luigi; Tramontano, Enzo; Canton, Serena; Corona, Angela; Scognamiglio, Sante; Paulis, Annalaura; Suleiman, Mustapha; Mohammed Al-Maqtari, Helmi; Abid, Fatma Mohamed A.; Kawsar, Sarkar M. A.; Sankaranarayanan, Murugesan; Di Santo, Roberto; Esposito, Francesca; Roberta Costi, And
Drug repurposing screen to identify inhibitors of the RNA polymerase (nsp12) and helicase (nsp13) from SARS-CoV-2 replication and transcription complex
2024-01-01 Kuzikov, Maria; Reinshagen, Jeanette; Wycisk, Krzysztof; Corona, Angela; Esposito, Francesca; Malune, Paolo; Manelfi, Candida; Iaconis, Daniela; Beccari, Andrea; Tramontano, Enzo; Nowotny, Marcin; Windshügel, Bjorn; Gribbon, Philip; Zaliani, Andrea
The antipsychotic drug lurasidone inhibits coronaviruses by affecting multiple targets
2024-01-01 Baroni, S.; Carletti, T.; Donalisio, M.; Arduino, I.; Cazzaniga, I.; Giorgino, T.; Esposito, Francesca; Porta, A.; Diomede, L.; De Luigi, A.; Gobbi, M.; Lembo, D.; Marcello, A.; Tramontano, Enzo; Milani, M.; Mastrangelo, E.
4-(3-Phenylsulfonylindol-2-yl)-1-(pyridin-2-yl)piperazinyl-methanones as Potent Inhibitors of both SARS-CoV-2 and HCoV-OC43 Viruses
2024-01-01 Puxeddu, M.; Donalisio, M.; Bugert, J. J.; Corona, Angela; Cocomazzi, P.; Milani, M.; Hucke, F.; Arduino, I.; Esposito, Francesca; Moretti, P.; Ortore, M. G.; Nalli, M.; Manetto, S.; Mazzoccanti, G.; Bigogno, C.; Dondio, G.; Scio, P.; Coluccia, A.; Fracella, M.; Antonelli, G.; Lembo, D.; Tramontano, Enzo; Silvestri, R.; Mastrangelo, E.; La Regina, G.
Special Issue “Advances in Antiviral Agents against SARS-CoV-2 and Its Variants”
2023-01-01 Esposito, Francesca
Targeting SARS-CoV-2 Main Protease: A Successful Story Guided by an In Silico Drug Repurposing Approach
2023-01-01 Alessandra Ambrosio, Francesca; Costa, Giosuè; Romeo, Isabella; Esposito, Francesca; Alkhatib, Mohammad; Salpini, Romina; Svicher, Valentina; Corona, Angela; Malune, Paolo; Tramontano, Enzo; Ceccherini-Silberstein, Francesca; Alcaro, Stefano; Anna Artese, And
DHFR Inhibitors Display a Pleiotropic Anti-Viral Activity against SARS-CoV-2: Insights into the Mechanisms of Action
2023-01-01 Iaconis, Daniela; Caccuri, Francesca; Manelfi, Candida; Talarico, Carmine; Bugatti, Antonella; Filippini, Federica; Zani, Alberto; Novelli, Rubina; Kuzikov, Maria; Ellinger, Bernhard; Gribbon, Philip; Riecken, Kristoffer; Esposito, Francesca; Corona, Angela; Tramontano, Enzo; Beccari, Andrea Rosario; Caruso, Arnaldo; Allegretti, Marcello
5-Nitro-3-(2-(4-phenylthiazol-2-yl)hydrazineylidene)indolin-2-one derivatives inhibit HIV-1 replication by a multitarget mechanism of action
2023-01-01 Corona, A.; Meleddu, R.; Delelis, O.; Subra, F.; Cottiglia, F.; Esposito, F.; Distinto, S.; Maccioni, E.; Tramontano, E.
HIV-1 Integrase Inhibition Activity by Spiroketals Derived from Plagius flosculosus, an Endemic Plant of Sardinia (Italy) and Corsica (France)
2023-01-01 Sanna, Cinzia; D’Abrosca, Brigida; Fiorentino, Antonio; Giammarino, Federica; Vicenti, Ilaria; Corona, Angela; Caredda, Alessia; Tramontano, Enzo; Esposito, Francesca
Nirmatrelvir treatment of SARS-CoV-2-infected mice blunts antiviral adaptive immune responses
2023-01-01 Fumagalli, Valeria; Di Lucia, Pietro; Ravà, Micol; Marotta, Davide; Bono, Elisa; Grassi, Stefano; Donnici, Lorena; Cannalire, Rolando; Stefanelli, Irina; Ferraro, Anastasia; Esposito, Francesca; Pariani, Elena; Inverso, Donato; Montesano, Camilla; Delbue, Serena; Perlman, Stanley; Tramontano, Enzo; De Francesco, Raffaele; Summa, Vincenzo; Guidotti, Luca G; Iannacone, Matteo
Strigolactones as broad-spectrum antivirals against β-coronaviruses through targeting the main protease Mpro
2023-01-01 Biolatti, Matteo; Blangetti, Marco; Baggieri, Melissa; Marchi, Antonella; Gioacchini, Silvia; Bajetto, Greta; Arnodo, Davide; Bucci, Paola; Fioravanti, Raoul; Kojouri, Maedeh; Bersani, Matteo; D’Arrigo, Giulia; Siragusa, Lydia; Ghinato, Simone; De Andre, Marco; Gugliesi, Francesca; Albano, Camilla; Pasquero, Selina; Visentin, Ivan; D’Ugo, Emilio; Esposito, Francesca; Malune, Paolo; Tramontano, Enzo; Prandi, Cristina; Spyrakis, Francesca; Magurano, Fabio; Dell’Oste, Valentina
Broad-spectrum coronavirus 3C-like protease peptidomimetic inhibitors effectively block SARS-CoV-2 replication in cells: Design, synthesis, biological evaluation, and X-ray structure determination
2023-01-01 Stefanelli, Irina; Corona, Angela; Cerchia, Carmen; Cassese, Emilia; Improta, Salvatore; Costanzi, Elisa; Pelliccia, Sveva; Morasso, Stefano; Esposito, Francesca; Paulis, Annalaura; Scognamiglio, Sante; Di Leva, Francesco Saverio; Storici, Paola; Brindisi, Margherita; Tramontano, Enzo; Cannalire, Rolando; Summa, Vincenzo
Dihydroxyphenyl- and Heteroaromatic-Based Thienopyrimidinones to Tackle HIV-1 LEDGF/p75-Dependent IN Activity
2023-01-01 Tocco, G.; Canton, S.; Laus, A.; Caboni, P.; Le Grice, S. F. J.; Tramontano, E.; Esposito, F.
Discovery of 2-Phenylquinolines with Broad-Spectrum Anti-coronavirus Activity
2022-01-01 Nizi, Maria Giulia; Persoons, Leentje; Corona, Angela; Felicetti, Tommaso; Cernicchi, Giada; Massari, Serena; Manfroni, Giuseppe; Vangeel, Laura; Barreca, Maria Letizia; Esposito, Francesca; Jochmans, Dirk; Milia, Jessica; Cecchetti, Violetta; Schols, Dominique; Neyts, Johan; Tramontano, Enzo; Sabatini, Stefano; De Jonghe, Steven; Tabarrini, Oriana
Cytopathic SARS-CoV-2 screening on VERO-E6 cells in a large-scale repurposing effort
2022-01-01 Zaliani, Andrea; Vangeel, Laura; Reinshagen, Jeanette; Iaconis, Daniela; Kuzikov, Maria; Keminer, Oliver; Wolf, Markus; Ellinger, Bernhard; Esposito, Francesca; Corona, Angela; Tramontano, Enzo; Manelfi, Candida; Herzog, Katja; Jochmans, Dirk; De Jonghe, Steven; Chiu, Winston; Francken, Thibault; Schepers, Joost; Collard, Caroline; Abbasi, Kayvan; Claussen, Carsten; Summa, Vincenzo; Beccari, Andrea R.; Neyts, Johan; Gribbon, Philip; Leyssen, Pieter
RiV4PoC: A high effective microbicidal coating for high-touch surfaces
2022-01-01 Angius, Fabrizio; Scano, Alessandra; Esposito, Francesca; Ennas, Guido; Manzin, Aldo
Easy access to α-ketoamides as SARS-CoV-2 and MERS Mpro inhibitors via the PADAM oxidation route
2022-01-01 Pelliccia, Sveva; Cerchia, Carmen; Esposito, Francesca; Cannalire, Rolando; Corona, Angela; Costanzi, Elisa; Kuzikov, Maria; Gribbon, Philip; Zaliani, Andrea; Brindisi, Margherita; Storici, Paola; Tramontano, Enzo; Summa, Vincenzo
Natural Compounds Inhibit SARS-CoV-2 nsp13 Unwinding and ATPase Enzyme Activities
2022-01-01 Corona, Angela; Wycisk, Krzysztof; Talarico, Carmine; Manelfi, Candida; Milia, Jessica; Cannalire, Rolando; Esposito, Francesca; Gribbon, Philip; Zaliani, Andrea; Iaconis, Daniela; Beccari, Andrea R.; Summa, Vincenzo; Nowotny, Marcin; Tramontano, Enzo
ANTIBACTERIAL COATING
2021-01-01 Scano, Alessandra; Ennas, Guido; Esposito, Francesca; Tramontano, Enzo; Angius, Fabrizio
Structural and biochemical analysis of the dual inhibition of mg-132 against sars-cov-2 main protease (Mpro/3clpro) and human cathepsin-l
2021-01-01 Costanzi, E.; Kuzikov, M.; Esposito, F.; Albani, S.; Demitri, N.; Giabbai, B.; Camasta, M.; Tramontano, E.; Rossetti, G.; Zaliani, A.; Storici, P.
In Vitro Anti-HIV-1 Reverse Transcriptase and Integrase Properties of Punica granatum L. Leaves, Bark, and Peel Extracts and Their Main Compounds
2021-01-01 Sanna, C.; Marengo, A.; Acquadro, S.; Caredda, A.; Lai, R.; Corona, A.; Tramontano, E.; Rubiolo, P.; Esposito, F.
Quinolinonyl Non-Diketo Acid Derivatives as Inhibitors of HIV-1 Ribonuclease H and Polymerase Functions of Reverse Transcriptase
2021-01-01 Messore, Antonella; Corona, Angela; Madia, Valentina Noemi; Saccoliti, Francesco; Tudino, Valeria; De Leo, Alessandro; Ialongo, Davide; Scipione, Luigi; De Vita, Daniela; Amendola, Giorgio; Novellino, Ettore; Cosconati, Sandro; Métifiot, Mathieu; Andreola, Marie-Line; Esposito, Francesca; Grandi, Nicole; Tramontano, Enzo; Costi, Roberta; Di Santo, Roberto
Identification of Inhibitors of SARS-CoV-2 3CL-Pro Enzymatic Activity Using a Small Molecule in Vitro Repurposing Screen
2021-01-01 Kuzikov, Maria; Costanzi, Elisa; Reinshagen, Jeanette; Esposito, Francesca; Vangeel, Laura; Wolf, Markus; Ellinger, Bernhard; Claussen, Carsten; Geisslinger, Gerd; Corona, Angela; Iaconis, Daniela; Talarico, Carmine; Manelfi, Candida; Cannalire, Rolando; Rossetti, Giulia; Gossen, Jonas; Albani, Simone; Musiani, Francesco; Herzog, Katja; Ye, Yang; Giabbai, Barbara; Demitri, Nicola; Jochmans, Dirk; De Jonghe, Steven; Rymenants, Jasper; Summa, Vincenzo; Tramontano, Enzo; Beccari, Andrea R.; Leyssen, Pieter; Storici, Paola; Neyts, Johan; Gribbon, Philip; Zaliani, Andrea
Exploring new scaffolds for the dual inhibition of HIV-1 RT polymerase and ribonuclease associated functions
2021-01-01 Meleddu, Rita; Corona, Angela; Distinto, Simona; Cottiglia, Filippo; Deplano, Serenella; Sequeira, Lisa; Secci, Daniela; Onali, Alessia; Sanna, Erica; Esposito, Francesca; Cirone, Italo; Ortuso, Francesco; Alcaro, Stefano; Tramontano, Enzo; Mátyus, Péter; Maccioni, Elias
Chemical Characterization and Anti-HIV-1 Activity Assessment of Iridoids and Flavonols from Scrophularia trifoliata
2021-01-01 Guzzo, Francesca; Russo, Rosita; Sanna, Cinzia; Celaj, Odeta; Caredda, Alessia; Corona, Angela; Tramontano, Enzo; Fiorentino, Antonio; Esposito, Francesca; D’Abrosca, Brigida
Targeting HIV-1 RNase H: N'-(2-Hydroxy-benzylidene)-3,4,5-Trihydroxybenzoylhydrazone as Selective Inhibitor Active against NNRTIs-Resistant Variants
2020-01-01 Corona, Angela; Ballana, Ester; Distinto, Simona; Rogolino, Dominga; Del Vecchio, Claudia; Carcelli, Mauro; Badia, Roger; Riveira-Muñoz, Eva; Esposito, Francesca; Parolin, Cristina; Esté, José A; Grandi, Nicole; Tramontano, Enzo
Development of a Raltegravir-based Photoaffinity-Labeled Probe for Human Immunodeficiency Virus-1 Integrase Capture
2020-01-01 Pala, Nicolino; Esposito, Francesca; Tramontano, Enzo; Kumar Singh, Pankaj; Sanna, Vanna; Carcelli, Mauro; Haigh, Lisa D.; Satta, Sandro; Mario Sechi, And
2-(Arylamino)-6-(trifluoromethyl)nicotinic Acid Derivatives: New HIV-1 RT Dual Inhibitors Active on Viral Replication
2020-01-01 Corona, Angela; Onnis, Valentina; Del Vecchio, Claudia; Esposito, Francesca; Cheng, Yung-Chi; Tramontano, Enzo
Probing the importance of the g-quadruplex grooves for the activity of the anti-hiv-integrase aptamer t30923
2020-01-01 Esposito, V.; Esposito, F.; Pepe, A.; Monterrey, I. G.; Tramontano, E.; Mayol, L.; Virgilio, A.; Galeone, A.
Discovery of dihydroxyindole-2-carboxylic acid derivatives as dual allosteric HIV-1 Integrase and Reverse Transcriptase associated Ribonuclease H inhibitors
2020-01-01 Esposito, Francesca; Sechi, Mario; Pala, Nicolino; Sanna, Adele; Koneru, Pratibha Chowdary; Kvaratskhelia, Mamuka; Naesens, Lieve; Corona, Angela; Grandi, Nicole; di Santo, Roberto; D'Amore, Vincenzo Maria; Di Leva, Francesco Saverio; Novellino, Ettore; Cosconati, Sandro; Tramontano, Enzo
Pyrrolyl Pyrazoles as Non-Diketo Acid Inhibitors of the HIV-1 Ribonuclease H Function of Reverse Transcriptase
2020-01-01 Messore, Antonella; Corona, Angela; Madia, Valentina Noemi; Saccoliti, Francesco; Tudino, Valeria; De Leo, Alessandro; Scipione, Luigi; De Vita, Daniela; Amendola, Giorgio; Di Maro, Salvatore; Novellino, Ettore; Cosconati, Sandro; Métifiot, Mathieu; Andreola, Marie-Line; Valenti, Piera; Esposito, Francesca; Grandi, Nicole; Tramontano, Enzo; Costi, Roberta; Di Santo, Roberto
Scaffold hopping and optimisation of 3’,4’-dihydroxyphenyl- containing thienopyrimidinones: synthesis of quinazolinone derivatives as novel allosteric inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H
2020-01-01 Tocco, Graziella; Esposito, Francesca; Caboni, Pierluigi; Laus, Antonio; Beutler, John A.; Wilson, Jennifer A.; Corona, Angela; Le Grice, Stuart F. J.; Tramontano, Enzo
Chromenone derivatives as a versatile scaffold with dual mode of inhibition of HIV-1 reverse transcriptase-associated Ribonuclease H function and integrase activity
2019-01-01 Esposito, F.; Ambrosio, F. A.; Maleddu, R.; Costa, G.; Rocca, R.; Maccioni, E.; Catalano, R.; Romeo, I.; Eleftheriou, P.; Karia, D. C.; Tsirides, P.; Godvani, N.; Pandya, H.; Corona, A.; Alcaro, S.; Artese, A.; Geronikaki, A.; Tramontano, E.
Dual HIV-1 reverse transcriptase and integrase inhibitors from Limonium morisianum Arrigoni, an endemic species of Sardinia (Italy)
2019-01-01 Sanna, Cinzia; Rigano, Daniela; Corona, Angela; Piano, Dario; Formisano, Carmen; Farci, Domenica; Franzini, Genni; Ballero, Mauro; Chianese, Giuseppina; Tramontano, Enzo; Taglialatela-Scafati, Orazio; Esposito, Francesca
On the S-layer of Thermus thermophilus and the assembling of its main protein SIpA
2018-01-01 Farci, Domenica; Farci, Stefano Francesco; Esposito, Francesca; Tramontano, Enzo; Kirkpatrick, Joanna; Piano, Dario
Identification of Myricetin as Ebolavirus VP35-dsRNA interaction inhibitor through a novel fluorescence-based assay
2018-01-01 Luca Daino, Gian; Frau, Aldo; Sanna, Cinzia; Rigano, Daniela; Distinto, Simona; Madau, Veronica; Esposito, Francesca; Fanunza, Elisa; Bianco, Giulia; Taglialatela-Scafati, Orazio; Zinzula, Luca; Maccioni, Elias; Corona, Angela; Tramontano, Enzo
Prenylated phloroglucinols from Hypericum scruglii, an endemic species of Sardinia (Italy), as new dual HIV-1 inhibitors effective on HIV-1 replication
2018-01-01 Sanna, Cinzia; Scognamiglio, Monica; Fiorentino, Antonio; Corona, Angela; Graziani, Vittoria; Caredda, Alessia; Cortis, Pierluigi; Montisci, Mariofilippo; Rita Ceresola, Elisa; Canducci, Filippo; Poli, Ferruccio; Tramontano, Enzo; Esposito, Francesca
Structure-guided approach identifies a novel class of HIV-1 Ribonuclease H inhibitors: Binding mode insights through magnesium complexation and site-directed mutagenesis studies
2018-01-01 Poongavanam, Vasanthanathan; Corona, Angela; Svendsen, Casper; Scipione, Luigi; Grandi, Nicole; Pandolfi, Fabiana; Di Santo, Roberto; Costi, Roberta; Esposito, Francesca; Tramontano, Enzo; Kongsted, Jacob
| Title | Issue Date | Author(s) | Journal | Publisher |
|---|---|---|---|---|
| 2‐Phenylquinolines Exhibit Anti‐Severe Acute Respiratory Syndrome Coronavirus‐2 Activity Through the Nonstructural Protein 13 Helicase Inhibition | 1-Jan-2026 | Cernicchi, Giada; Nizi, Maria Giulia; Emmolo, Roberta; Persoons, Leentje; Laporte, Manon; Jochmans, Dirk; Romeo, Isabella; Pepe, Giacomo; Milite, Ciro; Campiglia, Pietro; Spezzini, Jacopo; Martelli, Alma; Brogi, Simone; Esposito, Francesca; Felicetti, Tommaso; Massari, Serena; Manfroni, Giuseppe; Sabatini, Stefano; Sbardella, Gianluca; Alcaro, Stefano; Neyts, Johan; Corona, Angela; Tramontano, Enzo; De Jonghe, Steven; Tabarrini, Oriana | CHEMMEDCHEM | - |
| Special Issue “Advances in Antiviral Agents Against SARS-CoV-2 and Its Variants” 2nd Edition | 1-Jan-2026 | Esposito, Francesca | VIRUSES | - |
| Thiol-Reactive or Redox-Active: Revising a Repurposing Screen Led to a New Invalidation Pipeline and Identified a True Noncovalent Inhibitor Against Papain-like Protease from SARS-CoV-2 | 1-Jan-2025 | Kuzikov, Maria; Morasso, Stefano; Reinshagen, Jeanette; Wolf, Markus; Monaco, Vittoria; Cozzolino, Flora; Golič Grdadolnik, Simona; Šket, Primož; Plavec, Janez; Iaconis, Daniela; Summa, Vincenzo; Corona, Angela; Paulis, Annalaura; Esposito, Francesca; Tramontano, Enzo; Monti, Maria; Beccari, Andrea R.; Manelfi, Candida; Windshügel, Björn; Gribbon, Philip; Storici, Paola; Zaliani, Andrea | ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE | - |
| Identifying potential allosteric inhibitors of ZIKV NS3pro through a combined computational and biochemical approach | 1-Jan-2025 | Demuru, L.; Lupia, A.; Nieddu, S.; Emmolo, R.; Paulis, A.; Esposito, F.; Distinto, S.; Bryant, S. D.; Onali, A.; Sanna, E.; Atzeni, G.; Cottiglia, F.; Grandi, N.; Corona, A.; Tramontano, E.; Maccioni, E.; Meleddu, R. | - | - |
| 2-(Trihydroxyphenyl)thienopyrimidinones as Key Scaffolds for Targeting a Novel Allosteric Site of HIV-1 Integrase | 1-Jan-2025 | Tocco, Graziella; Laus, Antonio; Casula, Mattia; Caboni, Pierluigi; Beutler, John A.; Tramontano, Enzo; Esposito, Francesca | MOLECULES | - |
| Cys44 of SARS-CoV-2 3CLpro affects its catalytic activity | 1-Jan-2025 | Iacobucci, I.; Cipollone, I.; Cozzolino, F.; Iaconis, D.; Talarico, C.; Coppola, G.; Morasso, S.; Costanzi, E.; Malune, Paolo; Storici, P.; Tramontano, E.; Esposito, Francesca; Monti, M. | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | - |
| The efficiency of high-throughput screening (HTS) and in-silico data analysis during medical emergencies: Identification of effective antiviral 3CLpro inhibitors | 1-Jan-2025 | Zian, D.; Iaconis, D.; Nenci, S.; Crusco, A.; Tawde, S.; Sodano, M.; Vitalone, R.; Raje, A.; Palamini, M.; Carettoni, D.; Molteni, A.; Manelfi, C.; Tazzari, V.; Beccari, A. R.; Malune, P.; Maloccu, S.; Paulis, Annalaura; Corona, Angela; Nieddu, Salvatore; Coletti, S.; Scarabottolo, L.; Tramontano, Enzo; Esposito, Francesca; Catalani, M. | ANTIVIRAL RESEARCH | - |
| Meeting report: Seventh summer school on innovative approaches for identification of antiviral agents (IAAASS) | 1-Jan-2025 | Corona, Angela; Cagno, Valeria; Grandi, Nicole; Fanunza, Elisa; Esposito, Francesca; Seley-Radtke, Kathie L.; Tramontano, Enzo | ANTIVIRAL RESEARCH | - |
| Dual-Site Inhibition of SARS-CoV2 RNA-Dependent RNA Polymerase by Small Molecules Able to Block Viral Replication Identified through a Computer-Aided Drug Discovery Approach | 1-Jan-2025 | Malune, Paolo; Iaconis, Daniela; Manelfi, Candida; Giunta, Stefano; Emmolo, Roberta; Lunghini, Filippo; Paulis, Annalaura; Talarico, Carmine; Corona, Angela; Rosario Beccari, Andrea; Tramontano, Enzo; Esposito, Francesca | ACS INFECTIOUS DISEASES | - |
| Structure−Activity Relationships of New 1‐Aryl‐1H‐Indole Derivatives as SARS‐CoV‐2 Nsp13 Inhibitors | 1-Jan-2025 | Madia, Valentina Noemi; Emmolo, Roberta; Patacchini, Elisa; Amatore, Donatella; Maloccu, Stefania; Ialongo, Davide; Albano, Aurora; Ruggieri, Giuseppe; Cara, Emanuele; Zarbo, Laura; Messore, Antonella; De Santis, Riccardo; Amoroso, Alessandra; Lista, Florigio; Esposito, Francesca; Tramontano, Enzo; Corona, Angela; Di Santo, Roberto; Costi, Roberta | CHEMMEDCHEM | - |
| N -alkyl and N-benzyl indoles are anti-SARS-CoV-2 agents and nsp13 inhibitors | 1-Jan-2025 | Albano, Aurora; Emmolo, Roberta; De Santis, Riccardo; Patacchini, Elisa; Madia, Valentina Noemi; Maloccu, Stefania; Ialongo, Davide; Ruggieri, Giuseppe; Arpacioglu, Merve; Scipione, Luigi; Saccoliti, Francesco; Amatore, Donatella; Grilli, Giorgia; Lista, Florigio; Esposito, Francesca; Tramontano, Enzo; Corona, Angela; Di Santo, Roberto; Costi, Roberta | JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY | - |
| Unveiling SARS-CoV-2's heart: role, structure and inhibition of SARS-CoV-2 RNA-dependent RNA polymerase | 1-Jan-2025 | Malune, P.; Esposito, Francesca; Tramontano, E. | ANTIVIRAL RESEARCH | - |
| New Thiazolidine-4-One Derivatives as SARS-CoV-2 Main Protease Inhibitors | 1-Jan-2024 | Messore, Antonella; Malune, Paolo; Patacchini, Elisa; Noemi Madia, Valentina; Ialongo, Davide; Arpacioglu, Merve; Albano, Aurora; Ruggieri, Giuseppe; Saccoliti, Francesco; Scipione, Luigi; Tramontano, Enzo; Canton, Serena; Corona, Angela; Scognamiglio, Sante; Paulis, Annalaura; Suleiman, Mustapha; Mohammed Al-Maqtari, Helmi; Abid, Fatma Mohamed A.; Kawsar, Sarkar M. A.; Sankaranarayanan, Murugesan; Di Santo, Roberto; Esposito, Francesca; Roberta Costi, And | PHARMACEUTICALS | - |
| Drug repurposing screen to identify inhibitors of the RNA polymerase (nsp12) and helicase (nsp13) from SARS-CoV-2 replication and transcription complex | 1-Jan-2024 | Kuzikov, Maria; Reinshagen, Jeanette; Wycisk, Krzysztof; Corona, Angela; Esposito, Francesca; Malune, Paolo; Manelfi, Candida; Iaconis, Daniela; Beccari, Andrea; Tramontano, Enzo; Nowotny, Marcin; Windshügel, Bjorn; Gribbon, Philip; Zaliani, Andrea | VIRUS RESEARCH | - |
| The antipsychotic drug lurasidone inhibits coronaviruses by affecting multiple targets | 1-Jan-2024 | Baroni, S.; Carletti, T.; Donalisio, M.; Arduino, I.; Cazzaniga, I.; Giorgino, T.; Esposito, Francesca; Porta, A.; Diomede, L.; De Luigi, A.; Gobbi, M.; Lembo, D.; Marcello, A.; Tramontano, Enzo; Milani, M.; Mastrangelo, E. | FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY | - |
| 4-(3-Phenylsulfonylindol-2-yl)-1-(pyridin-2-yl)piperazinyl-methanones as Potent Inhibitors of both SARS-CoV-2 and HCoV-OC43 Viruses | 1-Jan-2024 | Puxeddu, M.; Donalisio, M.; Bugert, J. J.; Corona, Angela; Cocomazzi, P.; Milani, M.; Hucke, F.; Arduino, I.; Esposito, Francesca; Moretti, P.; Ortore, M. G.; Nalli, M.; Manetto, S.; Mazzoccanti, G.; Bigogno, C.; Dondio, G.; Scio, P.; Coluccia, A.; Fracella, M.; Antonelli, G.; Lembo, D.; Tramontano, Enzo; Silvestri, R.; Mastrangelo, E.; La Regina, G. | ACS INFECTIOUS DISEASES | - |
| Special Issue “Advances in Antiviral Agents against SARS-CoV-2 and Its Variants” | 1-Jan-2023 | Esposito, Francesca | VIRUSES | - |
| Targeting SARS-CoV-2 Main Protease: A Successful Story Guided by an In Silico Drug Repurposing Approach | 1-Jan-2023 | Alessandra Ambrosio, Francesca; Costa, Giosuè; Romeo, Isabella; Esposito, Francesca; Alkhatib, Mohammad; Salpini, Romina; Svicher, Valentina; Corona, Angela; Malune, Paolo; Tramontano, Enzo; Ceccherini-Silberstein, Francesca; Alcaro, Stefano; Anna Artese, And | JOURNAL OF CHEMICAL INFORMATION AND MODELING | - |
| DHFR Inhibitors Display a Pleiotropic Anti-Viral Activity against SARS-CoV-2: Insights into the Mechanisms of Action | 1-Jan-2023 | Iaconis, Daniela; Caccuri, Francesca; Manelfi, Candida; Talarico, Carmine; Bugatti, Antonella; Filippini, Federica; Zani, Alberto; Novelli, Rubina; Kuzikov, Maria; Ellinger, Bernhard; Gribbon, Philip; Riecken, Kristoffer; Esposito, Francesca; Corona, Angela; Tramontano, Enzo; Beccari, Andrea Rosario; Caruso, Arnaldo; Allegretti, Marcello | VIRUSES | - |
| 5-Nitro-3-(2-(4-phenylthiazol-2-yl)hydrazineylidene)indolin-2-one derivatives inhibit HIV-1 replication by a multitarget mechanism of action | 1-Jan-2023 | Corona, A.; Meleddu, R.; Delelis, O.; Subra, F.; Cottiglia, F.; Esposito, F.; Distinto, S.; Maccioni, E.; Tramontano, E. | FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY | - |
| HIV-1 Integrase Inhibition Activity by Spiroketals Derived from Plagius flosculosus, an Endemic Plant of Sardinia (Italy) and Corsica (France) | 1-Jan-2023 | Sanna, Cinzia; D’Abrosca, Brigida; Fiorentino, Antonio; Giammarino, Federica; Vicenti, Ilaria; Corona, Angela; Caredda, Alessia; Tramontano, Enzo; Esposito, Francesca | PHARMACEUTICALS | - |
| Nirmatrelvir treatment of SARS-CoV-2-infected mice blunts antiviral adaptive immune responses | 1-Jan-2023 | Fumagalli, Valeria; Di Lucia, Pietro; Ravà, Micol; Marotta, Davide; Bono, Elisa; Grassi, Stefano; Donnici, Lorena; Cannalire, Rolando; Stefanelli, Irina; Ferraro, Anastasia; Esposito, Francesca; Pariani, Elena; Inverso, Donato; Montesano, Camilla; Delbue, Serena; Perlman, Stanley; Tramontano, Enzo; De Francesco, Raffaele; Summa, Vincenzo; Guidotti, Luca G; Iannacone, Matteo | EMBO MOLECULAR MEDICINE | - |
| Strigolactones as broad-spectrum antivirals against β-coronaviruses through targeting the main protease Mpro | 1-Jan-2023 | Biolatti, Matteo; Blangetti, Marco; Baggieri, Melissa; Marchi, Antonella; Gioacchini, Silvia; Bajetto, Greta; Arnodo, Davide; Bucci, Paola; Fioravanti, Raoul; Kojouri, Maedeh; Bersani, Matteo; D’Arrigo, Giulia; Siragusa, Lydia; Ghinato, Simone; De Andre, Marco; Gugliesi, Francesca; Albano, Camilla; Pasquero, Selina; Visentin, Ivan; D’Ugo, Emilio; Esposito, Francesca; Malune, Paolo; Tramontano, Enzo; Prandi, Cristina; Spyrakis, Francesca; Magurano, Fabio; Dell’Oste, Valentina | ACS INFECTIOUS DISEASES | - |
| Broad-spectrum coronavirus 3C-like protease peptidomimetic inhibitors effectively block SARS-CoV-2 replication in cells: Design, synthesis, biological evaluation, and X-ray structure determination | 1-Jan-2023 | Stefanelli, Irina; Corona, Angela; Cerchia, Carmen; Cassese, Emilia; Improta, Salvatore; Costanzi, Elisa; Pelliccia, Sveva; Morasso, Stefano; Esposito, Francesca; Paulis, Annalaura; Scognamiglio, Sante; Di Leva, Francesco Saverio; Storici, Paola; Brindisi, Margherita; Tramontano, Enzo; Cannalire, Rolando; Summa, Vincenzo | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| Dihydroxyphenyl- and Heteroaromatic-Based Thienopyrimidinones to Tackle HIV-1 LEDGF/p75-Dependent IN Activity | 1-Jan-2023 | Tocco, G.; Canton, S.; Laus, A.; Caboni, P.; Le Grice, S. F. J.; Tramontano, E.; Esposito, F. | MOLECULES | - |
| Discovery of 2-Phenylquinolines with Broad-Spectrum Anti-coronavirus Activity | 1-Jan-2022 | Nizi, Maria Giulia; Persoons, Leentje; Corona, Angela; Felicetti, Tommaso; Cernicchi, Giada; Massari, Serena; Manfroni, Giuseppe; Vangeel, Laura; Barreca, Maria Letizia; Esposito, Francesca; Jochmans, Dirk; Milia, Jessica; Cecchetti, Violetta; Schols, Dominique; Neyts, Johan; Tramontano, Enzo; Sabatini, Stefano; De Jonghe, Steven; Tabarrini, Oriana | ACS MEDICINAL CHEMISTRY LETTERS | - |
| Cytopathic SARS-CoV-2 screening on VERO-E6 cells in a large-scale repurposing effort | 1-Jan-2022 | Zaliani, Andrea; Vangeel, Laura; Reinshagen, Jeanette; Iaconis, Daniela; Kuzikov, Maria; Keminer, Oliver; Wolf, Markus; Ellinger, Bernhard; Esposito, Francesca; Corona, Angela; Tramontano, Enzo; Manelfi, Candida; Herzog, Katja; Jochmans, Dirk; De Jonghe, Steven; Chiu, Winston; Francken, Thibault; Schepers, Joost; Collard, Caroline; Abbasi, Kayvan; Claussen, Carsten; Summa, Vincenzo; Beccari, Andrea R.; Neyts, Johan; Gribbon, Philip; Leyssen, Pieter | SCIENTIFIC DATA | - |
| RiV4PoC: A high effective microbicidal coating for high-touch surfaces | 1-Jan-2022 | Angius, Fabrizio; Scano, Alessandra; Esposito, Francesca; Ennas, Guido; Manzin, Aldo | - | - |
| Easy access to α-ketoamides as SARS-CoV-2 and MERS Mpro inhibitors via the PADAM oxidation route | 1-Jan-2022 | Pelliccia, Sveva; Cerchia, Carmen; Esposito, Francesca; Cannalire, Rolando; Corona, Angela; Costanzi, Elisa; Kuzikov, Maria; Gribbon, Philip; Zaliani, Andrea; Brindisi, Margherita; Storici, Paola; Tramontano, Enzo; Summa, Vincenzo | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| Natural Compounds Inhibit SARS-CoV-2 nsp13 Unwinding and ATPase Enzyme Activities | 1-Jan-2022 | Corona, Angela; Wycisk, Krzysztof; Talarico, Carmine; Manelfi, Candida; Milia, Jessica; Cannalire, Rolando; Esposito, Francesca; Gribbon, Philip; Zaliani, Andrea; Iaconis, Daniela; Beccari, Andrea R.; Summa, Vincenzo; Nowotny, Marcin; Tramontano, Enzo | ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE | - |
| ANTIBACTERIAL COATING | 1-Jan-2021 | Scano, Alessandra; Ennas, Guido; Esposito, Francesca; Tramontano, Enzo; Angius, Fabrizio | - | - |
| Structural and biochemical analysis of the dual inhibition of mg-132 against sars-cov-2 main protease (Mpro/3clpro) and human cathepsin-l | 1-Jan-2021 | Costanzi, E.; Kuzikov, M.; Esposito, F.; Albani, S.; Demitri, N.; Giabbai, B.; Camasta, M.; Tramontano, E.; Rossetti, G.; Zaliani, A.; Storici, P. | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - |
| In Vitro Anti-HIV-1 Reverse Transcriptase and Integrase Properties of Punica granatum L. Leaves, Bark, and Peel Extracts and Their Main Compounds | 1-Jan-2021 | Sanna, C.; Marengo, A.; Acquadro, S.; Caredda, A.; Lai, R.; Corona, A.; Tramontano, E.; Rubiolo, P.; Esposito, F. | PLANTS | - |
| Quinolinonyl Non-Diketo Acid Derivatives as Inhibitors of HIV-1 Ribonuclease H and Polymerase Functions of Reverse Transcriptase | 1-Jan-2021 | Messore, Antonella; Corona, Angela; Madia, Valentina Noemi; Saccoliti, Francesco; Tudino, Valeria; De Leo, Alessandro; Ialongo, Davide; Scipione, Luigi; De Vita, Daniela; Amendola, Giorgio; Novellino, Ettore; Cosconati, Sandro; Métifiot, Mathieu; Andreola, Marie-Line; Esposito, Francesca; Grandi, Nicole; Tramontano, Enzo; Costi, Roberta; Di Santo, Roberto | JOURNAL OF MEDICINAL CHEMISTRY | - |
| Identification of Inhibitors of SARS-CoV-2 3CL-Pro Enzymatic Activity Using a Small Molecule in Vitro Repurposing Screen | 1-Jan-2021 | Kuzikov, Maria; Costanzi, Elisa; Reinshagen, Jeanette; Esposito, Francesca; Vangeel, Laura; Wolf, Markus; Ellinger, Bernhard; Claussen, Carsten; Geisslinger, Gerd; Corona, Angela; Iaconis, Daniela; Talarico, Carmine; Manelfi, Candida; Cannalire, Rolando; Rossetti, Giulia; Gossen, Jonas; Albani, Simone; Musiani, Francesco; Herzog, Katja; Ye, Yang; Giabbai, Barbara; Demitri, Nicola; Jochmans, Dirk; De Jonghe, Steven; Rymenants, Jasper; Summa, Vincenzo; Tramontano, Enzo; Beccari, Andrea R.; Leyssen, Pieter; Storici, Paola; Neyts, Johan; Gribbon, Philip; Zaliani, Andrea | ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE | - |
| Exploring new scaffolds for the dual inhibition of HIV-1 RT polymerase and ribonuclease associated functions | 1-Jan-2021 | Meleddu, Rita; Corona, Angela; Distinto, Simona; Cottiglia, Filippo; Deplano, Serenella; Sequeira, Lisa; Secci, Daniela; Onali, Alessia; Sanna, Erica; Esposito, Francesca; Cirone, Italo; Ortuso, Francesco; Alcaro, Stefano; Tramontano, Enzo; Mátyus, Péter; Maccioni, Elias | MOLECULES | - |
| Chemical Characterization and Anti-HIV-1 Activity Assessment of Iridoids and Flavonols from Scrophularia trifoliata | 1-Jan-2021 | Guzzo, Francesca; Russo, Rosita; Sanna, Cinzia; Celaj, Odeta; Caredda, Alessia; Corona, Angela; Tramontano, Enzo; Fiorentino, Antonio; Esposito, Francesca; D’Abrosca, Brigida | MOLECULES | - |
| Targeting HIV-1 RNase H: N'-(2-Hydroxy-benzylidene)-3,4,5-Trihydroxybenzoylhydrazone as Selective Inhibitor Active against NNRTIs-Resistant Variants | 1-Jan-2020 | Corona, Angela; Ballana, Ester; Distinto, Simona; Rogolino, Dominga; Del Vecchio, Claudia; Carcelli, Mauro; Badia, Roger; Riveira-Muñoz, Eva; Esposito, Francesca; Parolin, Cristina; Esté, José A; Grandi, Nicole; Tramontano, Enzo | VIRUSES | - |
| Development of a Raltegravir-based Photoaffinity-Labeled Probe for Human Immunodeficiency Virus-1 Integrase Capture | 1-Jan-2020 | Pala, Nicolino; Esposito, Francesca; Tramontano, Enzo; Kumar Singh, Pankaj; Sanna, Vanna; Carcelli, Mauro; Haigh, Lisa D.; Satta, Sandro; Mario Sechi, And | ACS MEDICINAL CHEMISTRY LETTERS | - |
| 2-(Arylamino)-6-(trifluoromethyl)nicotinic Acid Derivatives: New HIV-1 RT Dual Inhibitors Active on Viral Replication | 1-Jan-2020 | Corona, Angela; Onnis, Valentina; Del Vecchio, Claudia; Esposito, Francesca; Cheng, Yung-Chi; Tramontano, Enzo | MOLECULES | - |
| Probing the importance of the g-quadruplex grooves for the activity of the anti-hiv-integrase aptamer t30923 | 1-Jan-2020 | Esposito, V.; Esposito, F.; Pepe, A.; Monterrey, I. G.; Tramontano, E.; Mayol, L.; Virgilio, A.; Galeone, A. | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - |
| Discovery of dihydroxyindole-2-carboxylic acid derivatives as dual allosteric HIV-1 Integrase and Reverse Transcriptase associated Ribonuclease H inhibitors | 1-Jan-2020 | Esposito, Francesca; Sechi, Mario; Pala, Nicolino; Sanna, Adele; Koneru, Pratibha Chowdary; Kvaratskhelia, Mamuka; Naesens, Lieve; Corona, Angela; Grandi, Nicole; di Santo, Roberto; D'Amore, Vincenzo Maria; Di Leva, Francesco Saverio; Novellino, Ettore; Cosconati, Sandro; Tramontano, Enzo | ANTIVIRAL RESEARCH | - |
| Pyrrolyl Pyrazoles as Non-Diketo Acid Inhibitors of the HIV-1 Ribonuclease H Function of Reverse Transcriptase | 1-Jan-2020 | Messore, Antonella; Corona, Angela; Madia, Valentina Noemi; Saccoliti, Francesco; Tudino, Valeria; De Leo, Alessandro; Scipione, Luigi; De Vita, Daniela; Amendola, Giorgio; Di Maro, Salvatore; Novellino, Ettore; Cosconati, Sandro; Métifiot, Mathieu; Andreola, Marie-Line; Valenti, Piera; Esposito, Francesca; Grandi, Nicole; Tramontano, Enzo; Costi, Roberta; Di Santo, Roberto | ACS MEDICINAL CHEMISTRY LETTERS | - |
| Scaffold hopping and optimisation of 3’,4’-dihydroxyphenyl- containing thienopyrimidinones: synthesis of quinazolinone derivatives as novel allosteric inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H | 1-Jan-2020 | Tocco, Graziella; Esposito, Francesca; Caboni, Pierluigi; Laus, Antonio; Beutler, John A.; Wilson, Jennifer A.; Corona, Angela; Le Grice, Stuart F. J.; Tramontano, Enzo | JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY | - |
| Chromenone derivatives as a versatile scaffold with dual mode of inhibition of HIV-1 reverse transcriptase-associated Ribonuclease H function and integrase activity | 1-Jan-2019 | Esposito, F.; Ambrosio, F. A.; Maleddu, R.; Costa, G.; Rocca, R.; Maccioni, E.; Catalano, R.; Romeo, I.; Eleftheriou, P.; Karia, D. C.; Tsirides, P.; Godvani, N.; Pandya, H.; Corona, A.; Alcaro, S.; Artese, A.; Geronikaki, A.; Tramontano, E. | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| Dual HIV-1 reverse transcriptase and integrase inhibitors from Limonium morisianum Arrigoni, an endemic species of Sardinia (Italy) | 1-Jan-2019 | Sanna, Cinzia; Rigano, Daniela; Corona, Angela; Piano, Dario; Formisano, Carmen; Farci, Domenica; Franzini, Genni; Ballero, Mauro; Chianese, Giuseppina; Tramontano, Enzo; Taglialatela-Scafati, Orazio; Esposito, Francesca | NATURAL PRODUCT RESEARCH | - |
| On the S-layer of Thermus thermophilus and the assembling of its main protein SIpA | 1-Jan-2018 | Farci, Domenica; Farci, Stefano Francesco; Esposito, Francesca; Tramontano, Enzo; Kirkpatrick, Joanna; Piano, Dario | BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES | - |
| Identification of Myricetin as Ebolavirus VP35-dsRNA interaction inhibitor through a novel fluorescence-based assay | 1-Jan-2018 | Luca Daino, Gian; Frau, Aldo; Sanna, Cinzia; Rigano, Daniela; Distinto, Simona; Madau, Veronica; Esposito, Francesca; Fanunza, Elisa; Bianco, Giulia; Taglialatela-Scafati, Orazio; Zinzula, Luca; Maccioni, Elias; Corona, Angela; Tramontano, Enzo | BIOCHEMISTRY | - |
| Prenylated phloroglucinols from Hypericum scruglii, an endemic species of Sardinia (Italy), as new dual HIV-1 inhibitors effective on HIV-1 replication | 1-Jan-2018 | Sanna, Cinzia; Scognamiglio, Monica; Fiorentino, Antonio; Corona, Angela; Graziani, Vittoria; Caredda, Alessia; Cortis, Pierluigi; Montisci, Mariofilippo; Rita Ceresola, Elisa; Canducci, Filippo; Poli, Ferruccio; Tramontano, Enzo; Esposito, Francesca | PLOS ONE | - |
| Structure-guided approach identifies a novel class of HIV-1 Ribonuclease H inhibitors: Binding mode insights through magnesium complexation and site-directed mutagenesis studies | 1-Jan-2018 | Poongavanam, Vasanthanathan; Corona, Angela; Svendsen, Casper; Scipione, Luigi; Grandi, Nicole; Pandolfi, Fabiana; Di Santo, Roberto; Costi, Roberta; Esposito, Francesca; Tramontano, Enzo; Kongsted, Jacob | MEDCHEMCOMM | - |
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