Simple squaramide receptors for highly efficient anion binding in aqueous media and transmembrane transport

Picci G.;Kubicki M.;Garau A.;Lippolis V.;Mocci R.;Porcheddu A.;Quesada R.;Ricci P. C.;Scorciapino M. A.;Caltagirone C.

2020-01-01

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Abstract

A family of acyclic squaramide receptors (L1-L5) have been synthesised with the aim to bind anions in a competitive solvent mixture and to evaluate how the presence of additional H-bond donor groups on the squaramide scaffold could affect the affinity towards anions and the transmembrane transport ability.