Preliminary study of bone tumors hyperthermia at microwaves using magnetic implants

Lodi, M. B.;Curreli, N.;Maccio, C.;Marongiu, E.;Mariani, L.;Fanti, A.;Bozzi, M.;Mazzarella, G.

2022-01-01

---

Abstract

Microwave hyperthermia as therapeutic modality in oncology can be the next breakthrough technology if translated properly to the clinical practice. For deep-seated tumors such as bone cancers, antennas and radiating sources fails in achieving therapeutic temperatures without overheating healthy tissues. In this framework, magnetic implant to be used as thermo-seeds exposed to a several kHz magnetic field were studied. So far, the possibility of using magneto-dielectric biocompatible implant for performing microwave hyperthermia was not studied. In this work, we propose a simplified mono-dimensional electromagnetic model to study the propagation in a multilayer structure by means of the wave-amplitude transmission method. The model is aimed at finding suitable properties of the bolus, to be used as matching medium, while determining a set of working frequency for performing an effective treatment using magnetic implants. Then, we investigate the temperature evolution to determine, preliminarily, the feasibility of this innovative treatment modality.