Tailoring MOFs to Biomedical Applications: A Chimera or a Concrete Reality? The Case Study of Fe-BTC by bio-friendly Mechanosynthesis

Giada Mannias;Alessandra Scano

Secondo

;Martina Pilloni;Edmond Magner;Guido Ennas

Ultimo

2023-01-01

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Abstract

We point-out an exceptional tailorability of iron(III) trimesate metal-organic framework to bio-friendly conditions. This is particularly attractive in sight of one-pot immobilization of biomolecules for biomedical applications. Synthesis is carried out via mechanochemical approach under green, biocompatible conditions without additional solvents, in just 1 hour, at room temperature. Solvents are proven to be unnecessary to build the framework, in contrast to solution-based methods. Microstructure and thermal stability of the material are not affected by pH. Conversely, textural properties can be tuned by simply varying the amount of base.