Exploring the efficacy and industrial potential of polyphenol products from grapes and their by-products

Rached, Rita Abi;Perra, Matteo;Manca, Maria Letizia;Rajha, Hiba N.;Louka, Nicolas;Maroun, Richard G.;Firoznezhad, Mohammad;Manconi, Maria

2024-01-01

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Abstract

Grapevines, renowned for their high phenolic content, are attracting significant interest due to their potential health benefits, including antioxidant, anti-inflammatory, and anti-cancer properties. This research delves deeply into the primary chemical constituents of grapes and their byproducts, identifying the most effective polyphenol extraction methods. Special emphasis is placed on the development and production of innovative grape-based formulations that enhance human health through various delivery methods such as cutaneous, mucosal, oral, pulmonary, and nasal. The transition from laboratory research to industrial production is also explored, highlighting the challenges and limitations of scaling up these novel health-promoting products. This comprehensive review aims at providing valuable insights into the potential of grape-derived compounds and their applications, paving the way for future innovations in the field of health and nutrition.