Impedance cardiography assessment during body immersion in a high concentrated water solution of magnesium chloride simulating space microgravity: a pilot study

Dell'Osa, AH;Fois, A;Cerina, A;Pili, F;Manuello Bertetto, A;Velluzzi, F;Bellomi, G;Palmas, M;Ruggiu, M;Melis, S;Tocco, F

;Concu, A

2025-01-01

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Abstract

In 14 healthy subjects (9 males and 5 females, 32±15 years) a beat-by-beat cardiodynamic profile was acquired with impedance cardiography during 10 minutes while lying supine and relaxed in a bed and then in a bath tub with a high concentration of MgCl2 reaching density 1/3 times more than sea. While in the tub, an increase in ventricular preload index (+47%) with reduction in contractility (-17%) and arterial pressure (-5%) occurred like as in space flights. So this method could be seen as a new way to simulating space fly at ground.